The authors report the case of a 40 year old man with a postero-inferi
or myocardial infarction. Echocardiography showed a large left atrial
myxoma. Coronary angiography performed 20 days after the onset of infa
rction was completely normal. The tumour was successfully removed surg
ically. The authors review the literature of this rare association (20
reported cases) which were commonly observed since the widespread use
of echocardiography and coronary angiography. These investigations ha
ve improved the understanding of the physiopathology of this associati
on. One of the possible hypotheses of diastolic mitral obstruction by
the tumour was the probable mechanism of infarction in this case due t
o prolonged impaired coronary filling due to low cardiac output.