This study examined whether employment status or job characteristics t
hought to be stressful were related to fibrinogen level in a sample of
161 healthy middle-aged women. Employed women had higher fibrinogen l
evels than did nonemployed women. Moreover, among employed women, thos
e who perceived high levels of job stress or low support from their bo
sses had elevated fibrinogen, independent of menopausal status. Percep
tion of low support from one's boss was related to higher fibrinogen l
evels only among premenopausal women or postmenopausal women who were
not using hormone replacement therapy. These results are consistent wi
th the notion that stress associated with some job characteristics inf
luences levels of fibrinogen in women.