ANESTHESIA AND CYSTIC-FIBROSIS

Cystic fibrosis occurs in 1 in 2000 children and the majority now reac h adulthood. The disease is a complex multisystem disorder which is li kely to challenge anaesthetists with increasing frequency. In this rev iew the presentation and genetics of the disease are briefly described , followed by a detailed account of the pathophysiology relevant to an aesthesia. The pre-operative assessment and conduct of anaesthesia are discussed and some suggestions made regarding management.