In the course of epidemiological and immunological baseline studies pa
rasitological surveys were conducted, in 1992, in three localities sit
uated in our near rain forest in the area of Lambarene, Gabon, western
Central Africa. Anopheles gambiae s.s. and A. funestus are considered
to be the main vectors of malaria. The three localities represent str
ata with obvious differences in the intensity of malaria transmission.
The lowest parasite rates were recorded in the village around the Alb
ert-Schweitzer-Hospital where environmental sanitation and easy access
to diagnostic and therapeutic facilities afford a fair measure of mal
aria control. The villages of Bellevue and Tchad show a much higher pr
evalence of Plasmodium falciparum, followed by P. malariae and P. oval
e. In all three villages parasite rates and geometric mean parasite de
nsities of P. falciparum showed the age pattern typical for areas with
stable, hyperendemic malaria. Analysis by season showed the period of
the long rains to be the epidemiologically calmest while the dry seas
on and even more the short rainy season produced an increase of parasi
te rates and densities. In Tchad, the most affected of the three villa
ges, the parasite rates in female adults were significantly lower than
in male adults. This was accompanied by lower parasite densities in f
emale adults.