Here we report the nucleotide sequence of the canine interleukin-2 (IL
-2)-encoding cDNA, Cloning of the canine IL-2 cDNA was achieved by the
polymerase chain reaction employing, as a template, a cDNA derived fr
om mitogen-stimulated canine splenic lymphocyte mRNA, The deduced amin
o acid (aa) sequence of canine IL-2 consists of 155 aa and displays 84
% sequence similarity to human IL-2.