Objective: To better define the spectrum of patient characteristics an
d fundus findings in patients with a presumably unique clinical entity
referred to as diabetic papillopathy. Design: Retrospective series. S
etting: A university-based referral practice. Methods: We retrospectiv
ely reviewed the medical records of all diabetic patients with benign,
transient disc swelling who were evaluated at our institution from 19
86 to 1992. Data pertaining to patient demographics, visual acuity and
symptoms, disc and retinal findings, ancillary test results, and clin
ical course were collected. Results: Twenty-seven eyes of 19 patients
met the study definition of diabetic papillopathy. Patients were gener
ally older (mean age, 50 years) and of a broader age range (19 to 79 y
ears) compared with those in prior reports. Two thirds of patients had
type II diabetes. Disc swelling was consistently hyperemic and, on av
erage, resolved within 3.7 months. Macular edema was a frequent associ
ated finding (70% of eyes) as was significant capillary nonperfusion (
52% of tested eyes). Only four eyes (15%) had final visual acuities of
less than 20/50 and each had prominent macular edema. Cup-disc ratio
analysis of uninvolved eyes revealed a significantly small physiologic
cup. Conclusions: The clinical profile of diabetic papillopathy can b
e expanded to include people who are older or have type II diabetes an
d that affected eyes commonly have macular edema or retinal vascular c
hanges that can adversely affect the visual outcome. Last, a small phy
siologic cup may represent an anatomic predisposition to the condition
.