We present the case of an elderly man with chronic obstructive pulmona
ry disease who had a 4-month history of multiple fluctuant masses of t
he dorsum of the right hand, which began at the site of an intravenous
catheter, Medications included inhaled and oral steroids. Fungal cult
ures of the fluid obtained grew a pigmented mold identified as Exophia
la species after several routine cultures were reported as negative. T
he patient underwent radical excision of the masses and received a per
ioperative course of oral itraconazole, This is one of the first known
cases of a possible nosocomially acquired phaeomycotic cyst. Unusual
fungi should be considered in the differential diagnosis of skin lesio
ns in immunocompromised patients.