IDENTIFICATION OF URINARY METABOLITES OF HUMAN-SUBJECTS EXPOSED TO O-DICHLOROBENZENE

o-Dichlorobenzene (o-DCB) has adverse effects on the liver and kidney in animals, It also causes some irritation to the eyes and the upper r espiratory system in humans, This study aimed to identify urinary meta bolites of human subjects exposed to o-DCB, Urine samples were collect ed from three male workers exposed to o-DCB and were analyzed using a gas chromatograph-mass spectrometer, 2,3- and 3,4-dichlorophenols and 3,4- and 4,5-dichlorocatechols were detected in the all samples, Some amounts of the four metabolites were presumably present as conjugates, because they increased after heating with hydrochloric acid.