RELEASE OF LH IN PIGS AFTER ADMINISTRATIO N OF THE GNRH AGONIST BUSERELIN IN COMPARISON TO D-PHE(6)-LHRH

Authors
MOLLERHOLTKAMP P STICKAN F PARVIZI N ELSAESSER F
Citation
P. Mollerholtkamp et al., RELEASE OF LH IN PIGS AFTER ADMINISTRATIO N OF THE GNRH AGONIST BUSERELIN IN COMPARISON TO D-PHE(6)-LHRH, Reproduction in domestic animals, 30(1), 1995, pp. 21-24
Citations number
19
Categorie Soggetti
Reproductive Biology","Veterinary Sciences
Journal title
Reproduction in domestic animals → ACNP
ISSN journal
09366768
Volume
30
Issue
1
Year of publication
1995
Pages
21 - 24
Database
ISI
SICI code
0936-6768(1995)30:1<21:ROLIPA>2.0.ZU;2-T
Abstract
The effect of various doses of buserelin and D-Phe(6)-LHRH on LH secre tion was tested in eight castrated male pigs. The preparations were gi ven intravenously and the administered dose of buserelin, as the activ e substance, was always one fifth of that of D-Phe(6)-LHRH. Both prepa rations produced a dose-related increase in LH secretion. The results indicate that the efficacy of buserelin in terms of LH release in the pig is five times that of D-Phe(6)-LHRH when expressed on the basis of the active substance in the preparation.