GDC (Guglielmi detachable coil)-embolization for the treatment of brai
n aneurysms was first published by Guglielmi in 1991 [1, 2] and has be
come an integral part of the treatment strategy for cerebral aneurysms
in many places around the world. Low morbidity and mortality rates [3
] are set against the limited possibilities of aneurysm neck occlusion
, especially in large necked aneurysms. Depending on the architecture
and on the kind of coil distribution, recanalization of the neck is mo
re or less frequent. Nevertheless, rebleeding rates are low [4]. In ou
r series of 211 brain aneurysms from March 1992 to June 1994, 74 (35%)
patients underwent GDC-embolization. 4 patients received combined tre
atment (GDC embolization and subsequent surgery). Follow-up angiograph
y was performed on 41 patients (55%) at periods of 6, 12, and 24 month
s (mean follow-up 8 months). To demonstrate the results in a graphic d
isplay, the aneurysms were grouped according to location and size. The
analysis of the follow-up results shows the highest occlusion stabili
ty in aneurysms of the basilar lip, followed by aneurysms of the PICA
origin, the basilar trunk and the PCA. Less stability was obtained in
aneurysms of the PCom followed by MCA, Acom and aneurysms of the inter
nal carotid (C1, ophthalmic). Aneurysms of the posterior circulation s
how generally better results than those located in the anterior circul
ation. This makes (in combination with the increased surgical difficul
ties of aneurysms in the posterior fossa) the GDC-treatment especially
useful for posterior circulation aneurysms.