D. Deboissieu et al., ALLERGY TO NONDAIRY PROTEINS IN MOTHERS MILK AS ASSESSED BY INTESTINAL PERMEABILITY TESTS, Revue francaise d'allergologie et d'immunologie clinique, 35(4), 1995, pp. 377-379
The intestinal permeability test is a noninvasive method which, when d
one during a food provocation procedure, can detect the deleterious ef
fect of food on the intestinal mucosa in allergic children. We report
on a 1-month-old breast-fed boy with a history of regurgitation, diarr
hea, difficult feeding, and malaise suggesting food allergy. Intestina
l permeability tests were done with the mother's milk and showed breas
t-milk-induced alterations of intestinal permeability. No improvement
occurred in the child's clinical symptoms or in the results of the int
estinal permeability test when the mother withdrew dairy products from
her diet. Disappearance of the child's symptoms and normalization of
intestinal permeability during provocation with the milk were obtained
after elimination of egg and pork from the mother's diet. This observ
ation suggests that dietary proteins different from cow's milk antigen
s may be transferred to breast milk and induce adverse reactions in hy
persensitive infants.