Rw. Baloh et al., PERSISTENT DIRECTION-CHANGING POSITIONAL NYSTAGMUS - ANOTHER VARIANT OF BENIGN POSITIONAL NYSTAGMUS, Neurology, 45(7), 1995, pp. 1297-1301
Positional nystagmus that does not fatigue, persists as long as the po
sition is held, and changes direction in different head positions has
typically been attributed to central vestibular lesions. We recently s
tudied three patients who presented with positional nystagmus having t
hese features but almost certainly of benign peripheral origin. All th
ree had an initial history typical of benign positional vertigo and, i
n two, the persistent direction-changing positional nystagmus occurred
after the patient underwent a maneuver to remove debris from the post
erior semicircular canal. The positional nystagmus profile and clinica
l course are consistent with the debris leaving the posterior semicirc
ular canal and becoming attached to the cupula of the horizontal semic
ircular canal.