DEVELOPMENT OF MINIMALLY DIFFERENTIATED ACUTE MYELOBLASTIC-LEUKEMIA WITH NOVEL ISOCHROMOSOME 18P AND ANTECEDENT APLASTIC-ANEMIA

Authors
KEUNG YK COBOS E MORGAN D TONK V
Citation
Yk. Keung et al., DEVELOPMENT OF MINIMALLY DIFFERENTIATED ACUTE MYELOBLASTIC-LEUKEMIA WITH NOVEL ISOCHROMOSOME 18P AND ANTECEDENT APLASTIC-ANEMIA, Cancer genetics and cytogenetics, 92(1), 1996, pp. 1-3
Citations number
22
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
92
Issue
1
Year of publication
1996
Pages
1 - 3
Database
ISI
SICI code
0165-4608(1996)92:1<1:DOMDAM>2.0.ZU;2-3
Abstract
We describe a case of acute myeloblastic leukemia with a novel isochro mosome 18, i(8)(p10), preceded by aplastic anemia for six months. The patient is a cotton grower chronically exposed to pesticides. The sign ificance of this chromosomal abnormality is unknown. The possible rela tionship to the preceding history of aplastic anemia and occupational pesticide exposure is speculated on. The possible mechanism of the ass ociation of acute leukemia and aplastic anemia is discussed. (C) Elsev ier Science Inc., 1996