Ka. Sullivan et al., GONADOTROPIN-RELEASING-HORMONE NEURONS IN THE RHESUS MACAQUE ARE NOT IMMUNOREACTIVE FOR THE ESTROGEN-RECEPTOR, Brain research, 685(1-2), 1995, pp. 198-200
The issue of whether gonadotropin-releasing hormone (GnRH) neurons in
the primate contain the estrogen receptor was examined by immunocytoch
emistry using prepubertal and adult (intact and ovariectomized) female
rhesus macaques. No GnRH neurons were found to contain nuclei that we
re immunoreactive for the estrogen receptor. These results confirm in
primates what has been reported in other species and leave open the qu
estion of how the effects of gonadal steroids on GnRH neurons are medi
ated.