OPHTHALMOSCOPY FOR CONGENITAL HYPERTROPHY OF THE RETINAL-PIGMENT EPITHELIUM (CHRPE) IN PATIENTS WITH SPORADIC COLORECTAL-CARCINOMA

Citation
A. Hartvigsen et al., OPHTHALMOSCOPY FOR CONGENITAL HYPERTROPHY OF THE RETINAL-PIGMENT EPITHELIUM (CHRPE) IN PATIENTS WITH SPORADIC COLORECTAL-CARCINOMA, International journal of colorectal disease, 10(3), 1995, pp. 138-139
Citations number
NO
Categorie Soggetti
Gastroenterology & Hepatology
ISSN journal
01791958
Volume
10
Issue
3
Year of publication
1995
Pages
138 - 139
Database
ISI
SICI code
0179-1958(1995)10:3<138:OFCHOT>2.0.ZU;2-7
Abstract
In order to investigate the frequency of congenital hypertrophy of the retinal pigment epithelium (CHRPE) in sporadic colorectal cancer, oph thalmoscopy was carried out in 34 patients with colorectal carcinoma w ithout known familial disposition. CHRPE is one of the most frequent e xtracolonic manifestations in familial adenomatous polyposis. None of the patients showed any sign of CHRPE. It is concluded that although g enetic factors are presumably of importance in the development of spor adic colorectal cancer, CHRPE cannot be used as a marker for future ri sk of colorectal carcinoma except in polyposis families.