EFFECT OF CADMIUM ON GROWTH AND PROTEIN-SYNTHESIS IN VIBRIO S14

Growth of Vibrio sp. strain S14 was inhibited by Cd2+ at concentration 8 mg.l(-1) provided that cadmium was added at initial growth phase. I f the same Cd2+ dose was applied to pre-adapted inoculum of cells, gro wth inhibition was not observed. An even more profound resistance of V ibrio 514 cells was achieved when Cd2+ ions were applied during expone ntial growth instead of the initial growth phase. Approximately 2 to 3 times higher uptake of C-14-glucose was observed into pre-stressed in comparison with non-adapted cells. Similar effect was achieved with s tarved cells exposed to subsequent toxic CdCl2 effect. Inhibition of p rotein synthesis in the pre-stress phase by chloramphenicol declared t he importance of de novo protein synthesis and its protective effect f or cell survival.