CORRELATION OF RENAL BIOPSY AND RADIONUCLIDE RENAL SCAN DIFFERENTIAL FUNCTION IN PATIENTS WITH UNILATERAL URETEROPELVIC JUNCTION OBSTRUCTION

Citation
Ja. Stock et al., CORRELATION OF RENAL BIOPSY AND RADIONUCLIDE RENAL SCAN DIFFERENTIAL FUNCTION IN PATIENTS WITH UNILATERAL URETEROPELVIC JUNCTION OBSTRUCTION, The Journal of urology, 154(2), 1995, pp. 716-718
Citations number
10
Categorie Soggetti
Urology & Nephrology
Journal title
ISSN journal
00225347
Volume
154
Issue
2
Year of publication
1995
Part
2
Pages
716 - 718
Database
ISI
SICI code
0022-5347(1995)154:2<716:CORBAR>2.0.ZU;2-#
Abstract
To understand better the relationship among radionuclide renal scan di fferential function, renal histology and the outcome of pyeloplasty we performed ipsilateral renal biopsies in a series of patients undergoi ng primary pyeloplasty. A total of 17 consecutive patients with unilat eral ureteropelvic junction obstruction underwent renal biopsy at the time of pyeloplasty. Biopsies were examined systematically after secti ons were stained with hematoxylin and eosin, periodic acid, Schiff, Jo nes modified silver or Masson trichrome stains, and they were reviewed by 1 pathologist. Biopsy results were correlated with preoperative an d postoperative radionuclide renal scan differential functions. Patien t age ranged from 1 month to 7 years (mean 19.8 months). Renal biopsy was abnormal in 6 kidneys, of which 5 had a preoperative differential function of less than 33%. None of these kidneys had evidence of posto perative improvement in renal function on followup scans despite a tec hnically successful result. All remaining 11 kidneys had normal biopsi es and a preoperative differential function of greater than 44%. We co nclude from these data that patients with ureteropelvic junction obstr uction with a differential function of less than 35% have a high proba bility of significant histological changes on biopsy and a low probabi lity of postoperative improvement in differential function.