Although male infants and young boys with epididymitis have a high inc
idence of anatomical pathology, dysfunctional voiding is not a well es
tablished cause of epididymitis. In our series 36 boys with epididymit
is underwent noninvasive urodynamic studies to determine whether a phy
siological defect could be assigned as an etiology. The 2 mechanisms p
roposed are similar to that in children with vesicoureteral reflux ass
ociated with dyssynergia or bladder instability and to a cause of recu
rrent urinary tract infection in children (the infrequent voider syndr
ome). Urinalysis and urine culture are recommended in all children wit
h epididymitis and urethral swabs are obtained from those who are sexu
ally active. We recommend renal/bladder ultrasound and voiding cystour
ethrography in all infants and young children with epididymitis. In th
e older child we advocate detailed questioning regarding voiding sympt
oms and the performance of noninvasive urodynamic studies.