INFLUENCE OF GENETIC-MARKERS ON THE ACTIV ITY OF GLUTATHIONE-PEROXIDASE IN ERYTHROCYTES AND ON THE CONCENTRATION IN THE SERUM OF SELENIUM IN SPANISH FIGHTING BULLS

In Spanish Fighting bulls after the fight and in females after the <<t ienra>>, (based on a simulated fight), a decrease in the activity of g lutathione peroxidase in erythrocytes and the concentration of seleniu m in serum is observed. The low levels of these parameters observed in this breed (including animals which have been fed with diets suppleme nted with selenium) led us to investigate whether a genetic factor cou ld explain this phenomenon. The effects of 37 genetic markers (7 Bioch emical polymorphisms and 30 antigens from 8 blood groups) on the conce ntration of the glutathione peroxidase in erythrocytes and selenium in serum have been studied in 179 bulls. To achieve it, 5 sistematic fac tors were used (season, body form, treatment of the bulls prior to the fight, punishment received by the bulls during the fight and the gene tic line to which the bulls belong to). The results show that the amyl ase and albumine have a significant effect on the activity of GSH-Px i n erythrocytes, and the genetic line has a very significant effect. Se rum transferrin, season, and the treatment of the animal prior to the fight have a very significant effect on the selenium concentration in blood. The observed variations suggest the possibility that generic fa ctors could influence GSH-Px activity in erythrocytes and environmenta l factors the concentration of serum selenium.