This paper reviews some of the main approaches to the analysis of mult
ivariate censored survival data. Such data typically have correlated f
ailure times. The correlation can be a consequence of the observationa
l design, for example with clustered sampling and matching, or it can
be a focus of interest as in genetic studies, longitudinal studies of
recurrent events and other studies involving multiple measurements. We
assume that the correlation between the failure or survival times can
be accounted for by fixed or random frailty effects. We then compare
the performance of conditional and mixture likelihood approaches to es
timating models with these frailty effects in censored bivariate survi
val data. We find that the mixture methods are surprisingly robust to
misspecification of the frailty distribution. The paper also contains
an illustrative example on the times to onset of chest pain brought on
by three endurance exercise tests during a drug treatment trial of he
art patients.