EXPERIMENTAL-VERIFICATION OF THEORETICAL IN-VIVO ULTRASOUND HEATING USING COBALT DETECTED MAGNETIC-RESONANCE

Conventional methods of measuring heating in vivo are invasive and the refore interfere with heat propagation. For the first time, ultrasound -induced temperature increases in living specimens have been estimated theoretically and measured experimentally using a noninvasive techniq ue, In vivo ultrasound-induced temperature increases in the livers of rats show consistent results between: (1) a theoretical ultrasound poi nt-source solution for a measured ultrasound source power of 4.3 W (2 degrees C) and (2) a sensitive noninvasive magnetic resonance method w ith the cobalt (Iii) nucleus as a probe (2.0 +/- 1.2 degrees C).