Thoracic nontuberculous or atypical mycobacterial infections typically
occur in patients who have underlying lung disease or an immunologic
abnormality. These infections are usually indolent and the diagnosis i
s often difficult to establish and, even if confirmed, is of questiona
ble clinical significance. The most common radiologic pattern is fibro
nodular opacities in the upper lobes similar to those seen with tuberc
ulosis. Less commonly, patients may have scattered nodularity associat
ed with bronchiectasis. If suspected by radiologic and clinical findin
gs, culture should be obtained for diagnosis. This review focuses on n
ontuberculous mycobacterial disease in the thorax of the immunocompete
nt host.