The intestines of 51 snakes with histologically diagnosed or suspected
amoebiasis were reinvestigated immunohistochemically with an Entamoeb
a invadens antibody. In 22 cases, trophozoites of Entamoeba invadens s
tained positively in the inflamed intestinal wall, but the protozoa vi
sible in the pathologically changed intestines of a further 20 snakes
were negative. On the basis of light and electron microscopical findin
gs, these protozoa were identified as flagellates.