AN ENANTIOCONTROLLED SYNTHESIS OF (-)-SWAINSONINE

Authors
KANG SH KIM GT
Citation
Sh. Kang et Gt. Kim, AN ENANTIOCONTROLLED SYNTHESIS OF (-)-SWAINSONINE, Tetrahedron letters, 36(28), 1995, pp. 5049-5052
Citations number
29
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
28
Year of publication
1995
Pages
5049 - 5052
Database
ISI
SICI code
0040-4039(1995)36:28<5049:AESO(>2.0.ZU;2-C
Abstract
(-)-Swainsonine 1, first isolated from the fungus Rhizoctonia legumini cola, has been sythesized enantioseletively. The key step was the ster eoselective iodoamination of trichloro-acetimidate derived from (Z)-ol efinic allylic alcohol 7.