APOLIPOPROTEIN-E AND APOLIPOPROTEIN-B ALLELES IN PARKINSONS PATIENTS

Authors
PODUSLO SE RIGGS D ROLAN T SCHWANKHAUS J
Citation
Se. Poduslo et al., APOLIPOPROTEIN-E AND APOLIPOPROTEIN-B ALLELES IN PARKINSONS PATIENTS, Neuroscience letters, 194(1-2), 1995, pp. 145-147
Citations number
15
Categorie Soggetti
Neurosciences
Journal title
Neuroscience letters → ACNP
ISSN journal
03043940
Volume
194
Issue
1-2
Year of publication
1995
Pages
145 - 147
Database
ISI
SICI code
0304-3940(1995)194:1-2<145:AAAAIP>2.0.ZU;2-I
Abstract
Parkinson's patients were genotyped for the apolipoprotein E alleles a s well as polymorphisms at the apolipoprotein B loci to determine whet her they were at risk for late onset Alzheimer's disease or coronary d isease. The Parkinson's patients were at no greater risk for either di sease than were the control spouses. The frequency for the APOE4 allel e was 11% compared with the spouses, 10%. Interestingly, 20% of the pa tients had the 2/3 genotype which may have a protective effect from la te onset Alzheimer's disease.