HISTOPATHOLOGY OF C57BL 6 MICE INOCULATED ORALLY WITH MYCOBACTERIUM-PARATUBERCULOSIS/

Authors
VEAZEY RS TAYLOR HW HOROHOV DW KRAHENBUHL JL OLIVER JL SNIDER TG
Citation
Rs. Veazey et al., HISTOPATHOLOGY OF C57BL 6 MICE INOCULATED ORALLY WITH MYCOBACTERIUM-PARATUBERCULOSIS/, Journal of Comparative Pathology, 113(1), 1995, pp. 75-80
Citations number
12
Categorie Soggetti
Pathology,"Veterinary Sciences
Journal title
Journal of Comparative Pathology → ACNP
ISSN journal
00219975
Volume
113
Issue
1
Year of publication
1995
Pages
75 - 80
Database
ISI
SICI code
0021-9975(1995)113:1<75:HOC6MI>2.0.ZU;2-1
Abstract
The susceptibility of C57BL/6 mice to oral inoculation with Myobacteri um paratuberculosis was evaluated histopathologically. Granulomatous l esions containing acid-fast bacteria developed in the mesenteric lymph nodes in over 50% of the mice by 11 months after inoculation. The res ults suggest that C57BL/6 mice may be useful for studying infection, p athogenesis, and other aspects of paratuberculosis. (C) 1995 Academic Press Limited