DIRECT PREPARATION AND MEIOTIC ANALYSIS OF HUMAN SEMEN

A meiotic study of human semen specimens was carried out in 60 cases. Among them, 20 were normal controls, 20 suffered from infertility, add 20 had a history of recurrent spontaneous abortions. Of the cases of infertility and abortion, 50% were found to have numerical and/or stru ctural chromosomal aberrations in spite of the normal blood karyotype. It is suggested that chromosomal aberrations may be the cause of ster ility and abortion. The success rate of semen chromosome G-banding in the infertility, abortion and control groups was 70%, 55% and 25% resp ectively. The semen samples of three cases of heterozygous carriers wi th reciprocal chromosomal translocation were also studied. The ring qu adrivalents were identified in all cases. The results may explain the recurrent abortions in these patients.