This paper describes the results concerning the effects of various dis
infectants on the oxygen uptake rate (OUR) of activated sludge (AS). T
o start with, in vitro inhibitory effects of four test disinfectants:
STERIHYDE(R), HYAMINE-T(R) ISODINE(R) and HYPAL No. 20(R), on OUR of t
wo kinds (AS-A; Kamaboko fishcake industrial waste water and AS-B; loc
al municipal sewage) of AS were determined by the previously mentioned
method.(2,3)) The IC50 values of thirty-three kinds of typical disinf
ectants were measured for AS-A, respectively. GRIhTCE(R), termed 2,4,4
'-trichloro-2'-hydroxydiphenyl ether (0.3% Irgasan DP 300), and Irgasa
n DP 300 alone, inhibited most strongly by the IC50 values of 6 mg/l,
respectively, and followed by Cetylpyridinium chloride (20 mg/l), OSVA
N'' (58 mg/l), KYAMINE-T(R) (58 mg/l), Potassium permanganate (60 mg/l
), Thimerosal (65 mg/l) and Benzethonium chloride (80 mg/l). However,
with Phenol, Suponated cresol, Resorcin, Silver nitrate, Medical soap,
Bronopol and Acrinol, the concentration of these disinfectants which
results in the IC50 value were over 1000 mg/l. In addition, the toxic
effects on OUR of AS in the presence of an equivalent mixture of two d
isinfectants tend to become stronger than that of the disinfectant alo
ne. Namely, the additive effects of OUR-inhibition seemed to exist (Fo
r example; Saponated cresol-STERIKYDE(R), HIBITANE(R) -GRINCI(R) etc.)
.