A GENERAL ALGORITHM TO COMPUTE MULTILOCUS GENOTYPE FREQUENCIES UNDER VARIOUS MATING SYSTEMS

This paper provides a general method to derive algebraic expressions o f genotype frequencies for multiple loci under various mating systems, including random mating, backcrossing, selfing, and full-sib mating. For each mating system, general equations are presented. In the case o f three loci, comprehensive tables provide recurrence equations for ge notype frequencies under random or self mating, and expected genotype frequencies after two generations of full-sib mating. Our results shou ld prove useful in genetic linkage analysis.