HIGHLY SELECTIVE AND PRACTICAL ALKYNE-ALKYNE CROSS-COUPLING USING CP(2)ZRBU(2) AND ETHYLENE

Authors
XI ZF HARA R TAKAHASHI T
Citation
Zf. Xi et al., HIGHLY SELECTIVE AND PRACTICAL ALKYNE-ALKYNE CROSS-COUPLING USING CP(2)ZRBU(2) AND ETHYLENE, Journal of organic chemistry, 60(14), 1995, pp. 4444-4448
Citations number
45
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
60
Issue
14
Year of publication
1995
Pages
4444 - 4448
Database
ISI
SICI code
0022-3263(1995)60:14<4444:HSAPAC>2.0.ZU;2-9
Abstract
Highly selective alkyne-alkyne cross coupling reactions were achieved using Cp(2)ZrBu(2) and ethylene gas. First, alkynes were treated with 1.2 equiv of Cp(2)ZrBu(2) (Negishi reagent) under ethylene gas to give zirconacyclopentenes with high selectivities. Subsequent addition of a second alkyne to the solution of zirconacyclopentenes at 50 degrees C gave unsymmetrical zirconacyclopentadienes selectively. After hydrol ysis unsymmetrical dienes were obtained in high yields.