Ce. Dubeau et al., CORRELATION BETWEEN MICTURITIONAL URETHRAL PRESSURE PROFILE AND PRESSURE-FLOW CRITERIA IN BLADDER OUTLET OBSTRUCTION, The Journal of urology, 154(2), 1995, pp. 498-503
Purpose: We correlate micturitional urethral pressure profilometry wit
h pressure-flow diagnoses of outlet obstruction. Materials and Methods
: Urodynamic evaluation was done of 86 consecutive men with voiding sy
mptoms. Obstruction criteria were a micturitional urethral pressure pr
ofile (MUPP) gradient greater than 5 cm. water, Schafer's linear passi
ve urethral resistance relation (PURR) greater than grade 1 and Abrams
-Griffiths nomogram. Results: Interpretable results were completed in
99% of the patients undergoing MUPP and 60% undergoing pressure-flow s
tudies (p < 0.00001). MUPP diagnosis agreed with PURR (p = 0.0015) and
Abrams-Griffiths nomogram results (p = 0.00004). MUPP gradients corre
lated well with PURR (r = 0.70, p < 0.00001). Using optimum cutoff val
ues (11 cm. water), the sensitivity of MUPP was 83%, specificity 82% a
nd positive predictive value 94%. Conclusions: MUPP correlates well wi
th and yields interpretable results more often than pressure-flow stud
ies.