T. Yamada et al., INFLUENCES OF NASAL RESPIRATORY OBSTRUCTION ON CRANIOFACIAL GROWTH INYOUNG MACACA-FUSCATA MONKEYS, American journal of orthodontics and dentofacial orthopedics, 111(1), 1997, pp. 38-43
This study was conducted to investigate the influences of artificial n
asal respiratory obstruction on craniofacial growth in young Macaca fu
scata monkeys. Eleven monkeys were used; seven monkeys served as the e
xperimental animals and the remaining four as the control animals. Fur
ther, the experimental animals were divided into light and heavy obstr
uction groups. Nasal respiratory obstruction was created by injecting
dental impression material into the nasopharyngeal region. Nasal respi
ratory function was evaluated in terms of nasal airway resistance. Cra
niofacial structure in the experimental monkeys was compared with the
control animals by means of cephalometric analysis, Nasopharyngeal res
piratory obstruction was associated with downward and backward rotatio
n of the mandible, upward and backward growth of the condyle, divergen
t gonial angle, anterior open bite, and spaced dental arch in the lowe
r anterior region, These changes were significantly greater in the exp
erimental monkeys with heavy respiratory obstruction, The current find
ings support the hypothesis that nasal obstruction existing before and
during pubertal growth may result in permanent craniofacial deformiti
es pertinent to skeletal open bite.