We describe the first case of pregnancy in a patient with amyotrophic
lateral sclerosis (ALS) reported in Uruguay. The 27-year-old white wom
an who came to our clinic complaining of general weakness and gait sym
ptoms was diagnosed as being pregnant and met the El Escorial criteria
of probable ALS. The advised abortion caused her to abandon medical t
reatment, which was only resumed after a period of severe deterioratio
n, at 32 weeks of gestation. After several days of serious vital risk,
as evaluated by a multidisciplinary team, a normal male baby was born
. Four months later, the patient had gradually improved and reached a
stable condition, but presented with restrictive ventilatory distress.