FACILE SYNTHESIS OF 1,4-BENZODIAZEPIN-5-ONE DERIVATIVES VIA INTRAMOLECULAR AZA-WITTIG REACTION - APPLICATION TO AN EFFICIENT SYNTHESIS OF O-BENZYL DC-81

Authors
EGUCHI S YAMASHITA K MATSUSHITA Y KAKEHI A
Citation
S. Eguchi et al., FACILE SYNTHESIS OF 1,4-BENZODIAZEPIN-5-ONE DERIVATIVES VIA INTRAMOLECULAR AZA-WITTIG REACTION - APPLICATION TO AN EFFICIENT SYNTHESIS OF O-BENZYL DC-81, Journal of organic chemistry, 60(13), 1995, pp. 4006-4012
Citations number
43
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
60
Issue
13
Year of publication
1995
Pages
4006 - 4012
Database
ISI
SICI code
0022-3263(1995)60:13<4006:FSO1DV>2.0.ZU;2-Q
Abstract
The tandem Staudinger/aza-Wittig reaction of N-(o-azidobenzoyl)-alpha- amino acid esters gave the corresponding 1,4-benzodiazepin-5-one deriv atives in moderate to good yields. This method was applied successfull y to a new efficient synthesis of BzlDC-81.