CILIARY BEAT FREQUENCY IS CONTROLLED BY A DYNEIN LIGHT-CHAIN PHOSPHORYLATION

Authors
SATIR P BARKALOW K HAMASAKI T
Citation
P. Satir et al., CILIARY BEAT FREQUENCY IS CONTROLLED BY A DYNEIN LIGHT-CHAIN PHOSPHORYLATION, Biophysical journal, 68(4), 1995, pp. 222-222
Citations number
2
Categorie Soggetti
Biophysics
Journal title
Biophysical journal → ACNP
ISSN journal
00063495
Volume
68
Issue
4
Year of publication
1995
Supplement
S
Pages
222 - 222
Database
ISI
SICI code
0006-3495(1995)68:4<222:CBFICB>2.0.ZU;2-A
Abstract
cAMP-dependent phosphorylation of a 29-kDa axonemal polypeptide (p29) increases the swimming speed of permeabilized Paramecium and in vitro translocation velocity of bovine brain microtubules over 22S dynein ex tracted from Paramecium axonemes. A quantitative relationship between microtubule translocation velocity and beat frequency is developed. We conclude that p29 acts as a regulatory light chain of outer arm dynei n in the control of ciliary beat frequency.