One hundred and fifty patients undergoing gastroduodenal surgery were
randomly allocated to receive intravenous (iv) cefuroxime, iv ciproflo
xacin or oral ciprofloxacin as prophylaxis. There were no differences
in the incidence of postoperative infection complications or duration
of stay among the three groups. Oral ciprofloxacin offers obvious adva
ntages in terms of ease of administration and cost.