DYSGERMINOMA OF THE OVARY IN A PATIENT WITH TRIPLE-X SYNDROME

A 24-year-old patient with dysgerminoma of the right ovary and hypopla stic left ovary was screened for chromosomal aberration, Triple-X synd rome was found in the oral epithelium and lymphocyte culture, while ch romosomal in situ hybridization of the tumor itself showed a normal XX karyotype. Although trisomy X and dysgerminoma are coincidental findi ngs in our case report, women with malignant germ cell tumors and abno rmal genitalia should be checked for chromosomal aberrations to exclud e anomalies carrying a Y chromosome.