LIPOPOLYSACCHARIDE AFFINITY FOR TITANIUM IMPLANT BIOMATERIALS

Statement of problem. Lipopolysaccharide (LPS) affinity for titanium i mplant biomaterials could affect crevicular LPS concentrations and the reby influence periimplant inflammation. Purpose of study. The purpose of this study was to evaluate Porphyromonas gingivalis and Escherichi a coli LPS affinity for titanium biomaterials groups that differed in surface oxide composition and surface roughness. Material and method. Polished and abraded grade 1 commercially pure titanium and grade 5 al loyed extra low interstitial titanium specimens were treated with 10 E U/mm(2) and radiolabeled LPS. Results. The resultant mean +/- SD LPS a dherence values ranged from 4.17 +/- 0.29 to 4.79 +/- 0.40 EU/mm(2). N o difference in adherence and elution was indicated on the basis of LP S type, surface oxide composition, or surface roughness. Moreover, P. gingivalis and E. coli LPS desorption was below detection. Conclusion. Clinically, the high affinity of both LPS types for titanium biomater ials may adversely influence the periimplant tissue response.