IMMEDIATE-EARLY GENES INDUCED BY ANTIGEN RECEPTOR STIMULATION

Authors
KELLY K SIEBENLIST U
Citation
K. Kelly et U. Siebenlist, IMMEDIATE-EARLY GENES INDUCED BY ANTIGEN RECEPTOR STIMULATION, Current opinion in immunology, 7(3), 1995, pp. 327-332
Citations number
45
Categorie Soggetti
Immunology
Journal title
Current opinion in immunology → ACNP
ISSN journal
09527915
Volume
7
Issue
3
Year of publication
1995
Pages
327 - 332
Database
ISI
SICI code
0952-7915(1995)7:3<327:IGIBAR>2.0.ZU;2-9
Abstract
Immediate early genes induced by triggering of the TCR frequently enco de proteins that act in signal transduction cascades. Recent advances concerning several immediate-early proteins have been made, including signal-induced regulation of NF-kappa B by I kappa-B, the role of Nur7 7 in T-cell selection and apoptosis, and the function of PAC-1 in regu lating the Ras/ERK pathway.