The past year has seen the publication of significant new findings on
the regulation of CD23 expression, the precise interaction of CD23 wit
h CD21 and its functional consequences. Moreover, new advances have be
en made in unravelling the biochemical network of events downstream fr
om the triggering of CD23 in human B cells. Analyses of the properties
of CD23-deficient mice have demonstrated a link between IgE regulatio
n and CD23 in vivo.