The risk of gallstones developing after gastrectomy in middle-aged Jap
anese men was investigated in a study of 2,738 men aged between 48 and
56 years who underwent both gallbladder ultrasonography (US) and a ba
rium study of the upper digestive tract. It was revealed that 61 men h
ad gallstones, 37 had had their gallbladder removed previously, and 55
had a history of gastrectomy. The prevalence of gallstones was 3.5 ti
mes higher in the men who had previously undergone gastrectomy (7.7%)
than in those who had not (2.2%) (P = 0.03). Moreover, gallstones tend
ed to be more prevalent in those who had undergone Billroth II gastrec
tomy (12.5%) compared with those who had undergone Billroth I gastrect
omy (5.6%); however, the difference was not significant. These results
indicate that gastrectomy using either Billroth I or Billroth IT reco
nstruction predisposes to gallstone formation. Nevertheless, it was es
timated that prior gastrectomy was responsible for no more than 5% of
gallstones in the study population.