Je. Richter, EXTRAESOPHAGEAL PRESENTATIONS OF GASTROESOPHAGEAL REFLUX DISEASE - THE CASE FOR AGGRESSIVE DIAGNOSIS AND TREATMENT, Cleveland Clinic journal of medicine, 64(1), 1997, pp. 37-45
Gastroesophageal reflux disease (GERD) has a number of extraesophageal
presentations, including noncardiac chest pain, asthma, and laryngiti
s. Although 24-hour esophageal pH monitoring is the best test to diagn
ose GERD, an empiric approach to treatment, using an aggressive acid s
uppression regimen such as a proton-pump inhibitor, may be more cost-e
ffective.