Ja. Schaffir et al., INCIDENCE OF PREGNANCY-INDUCED HYPERTENSION AMONG GESTATIONAL DIABETICS, American journal of perinatology, 12(4), 1995, pp. 252-254
Although hypertensive disorders of pregnancy are more likely to occur
in pregestational diabetics, the question of whether they occur more f
requently in gestational diabetics or certain subsets of gestational d
iabetics remains unclear. This study compared 197 gestational diabetic
s with 197 control patients matched on the basis of age, race, parity,
and prepregnancy weight. No significant difference was found between
the two groups in the incidence of either pregnancy-induced hypertensi
on or preeclampsia. There was, however, a small but significant elevat
ion in mean arterial blood pressure in the third trimester in gestatio
nal diabetics compared with control patients (90.1 versus 87.5 mm Hg;
p = 0.006). Mean arterial pressures were also higher in diabetic patie
nts on insulin compared with those on diet, and higher in diabetic pat
ients diagnosed early (less than 24 weeks) compared with those diagnos
ed late (more than 24 weeks) in pregnancy; however, there were larger
numbers of chronic hypertensives in these two groups. We conclude that
gestational diabetics do not develop pregnancy-induced hypertension m
ore frequently. Small increases in blood pressure late in pregnancy in
these patients achieve statistical significance, but their clinical r
elevance is unclear.