SYNTHESIS AND ANTI-HIV-1 ACTIVITY OF NEW THIADIAZEPINDIOXIDES

Authors
GIANNOTTI D VITI G NANNICINI R PESTELLINI V BELLAROSA D
Citation
D. Giannotti et al., SYNTHESIS AND ANTI-HIV-1 ACTIVITY OF NEW THIADIAZEPINDIOXIDES, Bioorganic & medicinal chemistry letters, 5(14), 1995, pp. 1461-1466
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
14
Year of publication
1995
Pages
1461 - 1466
Database
ISI
SICI code
0960-894X(1995)5:14<1461:SAAAON>2.0.ZU;2-S
Abstract
New pyridobenzo-and dipyridothiadiazepindioxides 3-5 and two isomers 1 3-14 were synthetized and their anti HIV-1 activity and the cytotoxici ty were evaluated in vitro. A good antiviral activity was shown by pyr idobenzothiadiazepindioxides 4, compound 4a being the best.