SELECTIVE KETALIZATION OF STEROIDAL 3,11,17-TRIONE USING CHLOROTRIMETHYLSILANE AS CATALYST

Authors
SU XD GAO HW HANG L LI ZS
Citation
Xd. Su et al., SELECTIVE KETALIZATION OF STEROIDAL 3,11,17-TRIONE USING CHLOROTRIMETHYLSILANE AS CATALYST, Synthetic communications, 25(18), 1995, pp. 2807-2811
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
25
Issue
18
Year of publication
1995
Pages
2807 - 2811
Database
ISI
SICI code
0039-7911(1995)25:18<2807:SKOS3U>2.0.ZU;2-8
Abstract
Selective ketalization of 13 beta-ethyl-gona-4-ene-3,11,17-trione (1) using chlorotrimethylsilane as catalyst afforded 13 beta-ethyl-gona-5- ene-3,11,17-trione-3-ethylene ketal (2) in fairly high yield. The corr esponding 3,17-diethylene ketal (3) was obtained in 70% yield when p-t oluenesulfonic acid was used as catalyst.