TITANIUM TETRACHLORIDE-MEDIATED CARBON-CARBON CHLOROCYANOETHYLATION OF ANISOLE - SYNTHESIS OF TYROSINE DERIVATIVES

Authors
HAZRA BG PORE VS BASU S
Citation
Bg. Hazra et al., TITANIUM TETRACHLORIDE-MEDIATED CARBON-CARBON CHLOROCYANOETHYLATION OF ANISOLE - SYNTHESIS OF TYROSINE DERIVATIVES, Synthetic communications, 25(18), 1995, pp. 2847-2855
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
25
Issue
18
Year of publication
1995
Pages
2847 - 2855
Database
ISI
SICI code
0039-7911(1995)25:18<2847:TTCCO>2.0.ZU;2-I
Abstract
Chlorocyanoethylation of anisole with 2-chloroacrylonitrile in presenc e of titanium tetrachloride furnished alpha-chloro-beta-(4-methoxyphen yl)propionitrile. This on simple reaction sequence was converted to (/-) thyl-alpha-amino-beta-(4-methonyphenyl)propionate, a tyrosine deri vative.