During initial clinical tests to calibrate our reflectance pulse oxime
try system, we observed serious physiologic limitations to the use of
pulse oximetry in the forehead region. We present a case of simultaneo
us reflectance and transmission mode pulse oximetry monitoring in a ch
ild undergoing cardiac surgery for congenital cyanotic heart disease w
ith a large intracardiac shunt. During general anesthesia, when the pa
tient was endotracheally intubated and mechanically ventilated, the tr
ansmission mode saturation agreed well with arterial oxygen saturation
measurements; but, our reflectance pulse oximeter, with the sensor ap
plied to the forehead, displayed spuriously lower (-18%) oxygen satura
tions. Before and after anesthesia and surgery, there was fine agreeme
nt between reflectance and transmission mode saturation values. We sug
gest that the difference was caused by vasodilatation and pooling of v
enous blood due to compromised venous return to the heart, and a combi
nation of arterial and venous pulsations in the forehead region. This
means that the reflectance pulse oximeter measured a mixed arterial-ve
nous oxygen saturation.