V. Beschkov et al., ION-EXCHANGE SEPARATION OF LACTIC-ACID FROM FERMENTATION BROTH, Hungarian journal of industrial chemistry, 23(2), 1995, pp. 135-139
The fermentation of lactose to lactic acid is usually accomplished by
strong product inhibition, leading to the process retardation and low
yields. In the present pal,er an attempt for the periodical removal of
lactate ions from the broth using an ion-exchange technique is made.
It is established that substrate conversion is considerably faster and
practically complete, compared to test experiments with pH control an
d without product removal. The possibility for feed-batch performance
of a bioreactor, coupled with ion-exchange column is studied and prove
d, too. Additional advantage of the studied technique is the recovery
of the product in a relatively pure and concentrated form as a sodium
salt.