Ds. Bardenstein et C. Elmets, HYPERFOCAL CRYOTHERAPY OF MULTIPLE MOLLUSCUM-CONTAGIOSUM LESIONS IN PATIENTS WITH THE ACQUIRED-IMMUNE-DEFICIENCY-SYNDROME, Ophthalmology, 102(7), 1995, pp. 1031-1034
Background: Patients with the acquired immune deficiency syndrome are
at risk for the development of multiple lesions of Molluscum contagios
um on the eyelids, In this setting, traditional methods of treatment f
requently are ineffective and pose risks to the patient as well as to
the treating physician. Methods: A technique was developed that combin
ed lidocaine/prilocaine topical anesthesia with hyperfocal cryotherapy
. Twelve patients with multiple M. contagiosum lesions of the eyelids
were treated. Initially, two methods were used: one application for 30
seconds or two applications for 20 seconds. Results: Lesions treated
with two 20-second applications regressed. Most of those lesions treat
ed for 30 seconds regressed. No scarring, lash complications, ptosis,
or damage to the underlying cornea or deeper ocular structures was obs
erved in any patient. Conclusions: Hyperfocal cryotherapy is an effect
ive therapy for multiple M. contagiosum lesions of the periorbital reg
ion, posing minimal risk to the patient and physician. It is particula
rly useful in patients who are positive for the human immunodeficiency
virus, who frequently have multiple lesions, are likely to have recur
rent disease, and who pose risks of disease transmission to the medica
l personnel caring for them.