COEXISTING LICHEN-PLANUS AND SUBACUTE CUTANEOUS LUPUS-ERYTHEMATOSUS

Authors
Citation
S. Grabbe et G. Kolde, COEXISTING LICHEN-PLANUS AND SUBACUTE CUTANEOUS LUPUS-ERYTHEMATOSUS, Clinical and experimental dermatology, 20(3), 1995, pp. 249-254
Citations number
28
Categorie Soggetti
Dermatology & Venereal Diseases
ISSN journal
03076938
Volume
20
Issue
3
Year of publication
1995
Pages
249 - 254
Database
ISI
SICI code
0307-6938(1995)20:3<249:CLASCL>2.0.ZU;2-X
Abstract
We report a patient who presented with annular erythematous skin lesio ns and generalized lichenoid papules. The clinical picture as well as histopathology, immunofluorescence and laboratory findings indicated c oexistence of subacute cutaneous lupus erythematosus (SCLE) and extens ive generalized lichen planus (LP). Clinically and histologically, SCL E-like lesions appeared to progress into LP-like lesions, supporting t he concept of a common autoimmune pathophysiology in these disorders. Treatment with cyclosporin A (2.5 mg/kg body weight) resulted in a sig nificant remission of the inflammatory skin lesions.